Estimation of adjusted minimal important differences for hip and knee replacement patients

Project description

One main goal of hip and knee replacements is to improve patients’ health-related quality of life (HRQoL). Thus, to properly assess treatment quality, it is crucial to understand which hip and knee replacements are successful in terms of changes in patient-reported HRQoL.  

A meaningful evaluation of treatment success can be achieved by calculating minimal important differences (MIDs) for changes in patient-reported outcome measures (PROMs). Evidence shows that considering patient characteristics is essential for calculating accurate MIDs.  

With this study we aim at estimating MIDs adjusted for patient characteristics for EQ-5D-3L index score improvements after hip and knee replacements. We contribute to the existing literature by relying on a large national sample and precise clustering algorithms.


Project team

Irene Salvi, Anja Bischof, Dr. David Kuklinski, Dr. Justus Vogel, Prof. Dr. Alexander Geissler 



Cooperation partner



Funding source




12 months (January 2023 to January 2024)